Cornelia De Langue Syndrome
NATIONAL JOURNAL OF HOMOEOPATHY 2004 Jan / Feb VOL VI NO 1.
Dr Jawahar Shah
'Medo

A child 14 months old, Master Sunder, was brought to me for delayed development.
The main complaints were of poor weight gain [5.5 kg]. Slow Mental development and slow milestones-no dentition or speech till date.

When I saw the patient for the first time, his face, expressions and movements were like that of a small baby monkey. He had plenty of hair all over his body +10. He had bushy eyebrows, long eyelashes, a small nose and thin drawn up legs - features evident of Hirsuitism ++.

Life Situation:
Mother had tremendous tension and worry during pregnancy.Main cause-Future Dowry. The mother came from a community where a girl has to be given heavy dowry; the mother, therefore, wanted a male child. She always worried what if she got a girl. Her sleep was disturbed 3+ and she had severe complaints of acidity 3+ and vomiting 3+ during this period. She would start in sleep, worry 3 at night and often dreamt that someone was harming her. She felt neglected during pregnancy as there was not much of co-operation from her husband.
(In the past, she had got an amniocentesis done and had abortion, since it was a female child)

Personal history
Appetite-Less
Craving-Sweets +3
Bowel-Constipated, passes stool every alternate day.
Feels better after burping; otherwise vomits.
Sweat-+++ fan is must, likes air conditioning
Urine-Nil
Sleep-Gets up with a startle; when patted goes back to sleep.
Thermal modality:Hot
Bath-Tepid. Cover-Aversion
Weather-Comfortable in winter

Past history
Birth weight 2.2 Kg. P/H/O. Bronchitis, cold, cough, constipation frequently Cleft palate-operated 3 months back. Tongue tie-operated
F/H: Mother-Cold++. MGF-Diabetes

Clinical Examination
O/E Flat head, fontanelles open.
Hair +10- face, back and all over body, Eyebrows bushy. Hirsuitism.
Undescended testes ++ bilateral.

Diagnosis: of this syndrome in the case of Sunder was based on following criteria:

1. Low birth weight.
2. Facial features-like that of monkey, small head, hair growth, eye brows bushy, etc.
3. Hirsuitism.
4. Undescended testicles.
5. Congenital anomalies-cleft lip and palate
6. Language delay.
7. Growth retardation, no teething, etc.
8. Behavioural problems.
9. Poor sleep and appetite.
10. Mental retardation.

Diagnosis:
Congenital Anomalies, Microcephaly. Cornelia De Lange Syndrome.
1/6/93 Medo 30 3P N SL pill TDS
7/6/93 Playful Active +
Follows object and movements.Makes and attempt to get up. Rx SL
14/6/93 Recognizes small objects like mango, etc.
Activity>> Rx SL
21/6/93 Tooth eruption ++ Rx SL
30/6/93 Turns, recognizes +5 Active on rolls++
Wants to go out. Smiles.When taken out and brought back,sees home and start crying.Recognizes and shows finger to go out.Extra hair has started falling.Rx SL 1-1 for 3 months
11/11/93 Improvement ++++
Can recognize people/objects,mixes around with everyone.Can do many things on his own. Rx SL
12/12/94 Improvement continues. Hair fall +5
Can recognize more objects.Differentiates taste. Rx SL
21/4/2001 Patient is alive till last known with considerable improvement in over all performance mentally and physically.
Patient is 9 yrs old, weight of child is 12 kg and mental age is of four and a half years.

Following improvement observed in the child:

• Can understand instructions in three languages,English, Gujarati and Hindi.
• Understands commands well.
• Recognizes voices of family, friends and makes an attempt to speak on phone.
• Can hold pencil and scribble.
• Makes signals and gestures for whatever he wants
• Likes to keep things in order.
• Sensitive and moody in nature.
• Loves to mix with older people.
• Has developed a good coordination between picture and words.
• Sleeps well.
• Loves to listen to music.
• Can play with beats and rhythms.
• Can play with others.
• Desire to travel, to go out, meet people.
• Shows way out of the house.
• Recognizes good clothes and appreciates with positive gestures.
• Loves cold drinks, Mac Donald’s food and insists mother to give such food.
• Whenever there is a pit, understands and moves accordingly.

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